Discipline: Technology and Engineering
Subcategory: Biomedical Engineering
Room: Marriott Balcony A
Jacori Small - Delaware State University
Co-Author(s): Dr. Adam Mazurkiewicz, UTP University of Science & Technology, Bydgoszcz, Poland 85789
The human body endures various amounts of load during daily activities. During these daily activities such as breathing, walking or running the human bones are forced to withstand different loads. These loads can vary based on the individuals’ environment. The bone studied in this experiment is bovine cortical bone from a cow. Cortical bone can be found on the outermost layer of a bone. It functions to protect the internal cavity of the bone. When studying mechanical test on bone it is essential that the bone is properly stored, so it doesn’t degrade. Therefore, the purpose of this experiment was to determine the influence of three storage methods on cortical bone and analyze if the mechanical properties varied overtime. This study included 30 bovine cortical bone samples. Each bone sample was cut into 10x10mm cubes. Next, the samples were divided into three groups of ten and underwent a compression test via the Instron E3000. After, they were immediately stored in their respective solution and temperature. Ten samples were tested for each storage method. The storage methods chosen for this experiment include: 96% Alcohol at 21°C, Sodium Chloride at -26°C and 10% Formalin at 21°C. All of the samples were stored for seven days. After seven days the samples were subject to the same compression test. We hypothesized that all three storage methods would show an insignificant change of the cortical bone overtime. The statistical results were calculated by utilizing the Wilcoxon test. The results show that storage in Alcohol and Sodium Chloride have significant effects on cortical bone, while Formalin shows insignificant change. In conclusion, the solution and temperature in which the bone sample is stored do play a major role in preservation. In the future, experiments with larger sample sizes and a longer storage interval will be considered, which would lead to more accurate results. Samples will also be collected from various cows, rather than from one cow.
Funder Acknowledgement(s): Dr. Adam Mazurkiewicz (Mechanical Engineering Department) UTP University of Science & Technology, Bydgoszcz, Poland Dr. Mazen Shahin (LSAMP Director) Delaware State University, Dover, Delaware The Greater Philadelphia Region Louis Stokes Alliance for Minority Participation The National Science Foundation12/11/2019 Dr. Mazen Shahin (LSAMP Director); Delaware State University, Dover, Delaware The Greater Philadelphia Region Louis Stokes Alliance for Minority Participation The National Science Foundation
Faculty Advisor: Dr. Mazen Shahin, email@example.com
Role: I completed the research by myself. However, my research advisor helped with any questions I may have had while conducting the research.