Emerging Researchers National (ERN) Conference

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Development of Rhodium Catalyzed Carbon-Carbon Bond Formation in the Synthesis of Bipyridines

Faculty #10
Discipline: Chemistry & Chemical Sciences
Subcategory: STEM Research

Fenghai Guo - Winston Salem State University
Co-Author(s): Briana N. Graves, Jeffires Malcolm, and Shekinah Graham WSSU


Heterocycles account for more than 50% of all known organic compounds synthesized both by nature and chemists. Heterocycles or heterocycle subunits are also present in over 75% of the top 200 brand name drugs are. Heterocycles have continued to be the focus of intense synthetic activity both in academia and industry. Many synthetic methods including metal catalyzed reactions have been developed in the efforts to synthesize heterocycles. Metal catalyzed carbon carbon bond formation is very valuable in forming the carbon skeletons of complex heterocycle synthesis. Rhodium catalyzed carbon carbon bond formation reactions using arylboronic acid/organometallic reagents in heterocyclic compounds such as benzopyrans have been developed. We are also interested in applying this new C-C bond formation strategy to the synthesis of pyridines and bipyridines.

Funder Acknowledgement(s): HBCU-UP RIA Award

Faculty Advisor: None Listed,

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This material is based upon work supported by the National Science Foundation (NSF) under Grant No. DUE-1930047. Any opinions, findings, interpretations, conclusions or recommendations expressed in this material are those of its authors and do not represent the views of the AAAS Board of Directors, the Council of AAAS, AAAS’ membership or the National Science Foundation.