Discipline: Biological Sciences
Subcategory: Cell and Molecular Biology
Kamaria A. Bush - North Carolina Agricultural and Technical State University
The diagnosis of microbial lineages from genomic and metagenomic data has been an active and worldwide area of development. We are developing a well-calibrated approach to integrating software tools with GALAXY. These software tools include Breseq and Metaphlan. The GALAXY bioinformatics environment provides for saving and reutilization of both datasets as well as the steps and parameters of assoociated workflows for analysis. Our case study has been to investigate short read data of DNA sequences generated from three different strains of bacteria, and build a workflow in GALAXY that can evaluate for the likely type of bacteria associated with the data and guide the identification and interpretation of likely mutations. This effort is guiding objectives in analysis, training, and implementation within the bioinformatics infrastructure of our university.Not Submitted
Funder Acknowledgement(s): HBCU-UP ACE Data Science and Analytics (DSA) Program
Faculty Advisor: Scott H. Harrison, email@example.com
Role: Analyzing the strains for mutation patterns, using Breseq. Created a workflow using GALAXY. Identify the strains of the bacteria with MetaPhlAn.