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Comparative Metabolite Analysis of Azadirachta Indica and Closely Related Species Melia Azedarach

Undergraduate #152
Discipline: Biological Sciences
Subcategory: Plant Research

Cybrena Nonetta Sablon - Bowie State University


Azadirachta indica is a medicinal tree in the mahogany family, native to southern Asia. It is often confused with a close relative, Melia azedarach. There are a lot of literature reports on the benefits of A. indicia, Neem. This plant has been regarded as ‘village dispensary ‘ in Kenya, where it has a local name, ‘Mwarubaine’ which means forty (40) because it is believed to manage forty disease conditions. The importance of the Neem tree has been recognized by the US National Academy of Sciences, which published a report in 1992 entitled, Neem: a tree for solving global problems. This research project was focused on finding distinguishing chemical differences and similarities between the species. This was done to help clarify the confusion between both plants by highlighting the chemical differences that set them apart. With the utilization of High-Pressure Thin Layer Chromatography (HPTLC) chemical differences and similarities of both plants can be visually observed. The differing bands show that there are chemical differences in the leaves. These differences are shown in the absence and presence of bands in different samples, as well as color differences in the bands.

Not Submitted

Funder Acknowledgement(s): National Science Foundation

Faculty Advisor: Dr. Anne OSano, asano@bowiestate.edu

Role: All of it.

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This material is based upon work supported by the National Science Foundation (NSF) under Grant No. DUE-1930047. Any opinions, findings, interpretations, conclusions or recommendations expressed in this material are those of its authors and do not represent the views of the AAAS Board of Directors, the Council of AAAS, AAAS’ membership or the National Science Foundation.

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