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The Synthesis and UV-Visible Spectral Characterization of Meso-Tetrakis (5-Bromo-2-Hydroxy-3-Methodoxy) Porphyrin: A Potential Anticancer Drug

Undergraduate #170
Discipline: Chemistry and Chemical Sciences
Subcategory: Cancer Research

Zari Preyer - Savannah State University
Co-Author(s): Dr. Adegboye Adeyemo



A new photosensitizing agent, Meso-Tetrakis (5-Bromo-2-hydroxy-3-methoxyphenyl) porphyrin, has been prepared. Some of the metal derivatives of the new photosensitizer were also investigated. Both the photosensitizing agent and its metal derivatives were characterized spectrophotometrically. Results show a marked difference between the free base and its metal derivatives. We present and discuss the similarities and differences in the spectra and spectral data of the free base and its metal derivatives.

Corret Abstract.docx

Funder Acknowledgement(s): NIH-National Institute of Health ; RISE-Research Institute for Scientific Enhancement Program

Faculty Advisor: Dr. Adegboye Adeyemo, adeyemoa@savannahstate.edu

Role: Synthesis of Porphyrin ; Synthesis of Metalloporphyrins ; Characterization of Porphyrin using UV Spectrophotometer ; Purification of porphyrin Thin Layer Chromatography; Purification of porphyrin using Column Chromatography

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This material is based upon work supported by the National Science Foundation (NSF) under Grant No. DUE-1930047. Any opinions, findings, interpretations, conclusions or recommendations expressed in this material are those of its authors and do not represent the views of the AAAS Board of Directors, the Council of AAAS, AAAS’ membership or the National Science Foundation.

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