Discipline: Social, Behavioral, and Economic Sciences
Subcategory: Pollution/Toxic Substances/Waste
Session: 2
Room: Exhibit Hall A
Kayla Gamble - Claflin University
Glyphosate is the main chemical material in the well-known herbicide Roundup. Glyphosate inhibits the shikimate pathway in plants. This pathway consumption increases the risks of diseases and disorders such as breast cancer, thyroid cancers, and autism. The amount of Roundup that is used every day, is so much that it can potentially contaminate our food supply. The purpose of this research was to examine the effect of Roundup on the morphology of female neuronal cells in culture. Cells were incubated in different concentrations of glyphosate and stained with Hematoxylin and Eosin after 24 hours. Images were taken and analyzed for axonal thinning, axonal degeneration and chromatolysis. The significance was calculated using a student t-test (P<0.05). We found that treated cells had significantly more chromatolysis but not axonal thinning and degeneration than untreated cells. The future experiment is continuing to analyze the effects of roundup has on Human Developing Neurons.
Funder Acknowledgement(s): MADE in SC, and School of Natural Sciences and Mathematics of Claflin University
Faculty Advisor: Omar Bagasra, obagasra@claflin.edu
Role: Research of the topic, the experiment; took the cell line (2266) grew & took care of the cells then eventually dilute with the roundup, staining, and analyzing the data